Hemodialysis and its effects on glymphatic system function in end-stage kidney disease patients

ESKD patients exhibited a significantly lower ALPS index compared with HCs, indicating altered perivascular diffusion patterns. No significant changes in the ALPS index were detected after a single hemodialysis session. As the ALPS index is an indirect marker, further research is needed to clarify its relationship with glymphatic function in kidney disease.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-10-29
DOI
https://doi.org/10.21037/qims-2025-74
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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article

Hemodialysis and its effects on glymphatic system function in end-stage kidney disease patients

Zhenliang Xiong, Tianliang Shi, Min Wu, Peng Wang et al.
Quantitative Imaging in Medicine and Surgery
Cerebrospinal fluid and hydrocephalus
article

Hemodialysis and its effects on glymphatic system function in end-stage kidney disease patients

Zhenliang Xiong, Tianliang Shi, Min Wu, Peng Wang, Xian‐Chun Zeng, Jin Yang, Jiancheng Zhang, Rongpin Wang
article en

Abstract

ESKD patients exhibited a significantly lower ALPS index compared with HCs, indicating altered perivascular diffusion patterns. No significant changes in the ALPS index were detected after a single hemodialysis session. As the ALPS index is an indirect marker, further research is needed to clarify its relationship with glymphatic function in kidney disease.

Quantitative Imaging in Medicine and SurgeryVol. 15(11)
Guizhou University (CN), Tongren Hospital (CN), Guizhou Provincial People's Hospital (CN)
Openalex Percentile: Top 66%
Cerebrospinal fluid and hydrocephalus
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