Ultrafast breast DCE-MRI: comparative analysis of semi-quantitative and pharmacokinetic parameters with gadoterate meglumine versus gadobutrol in malignant lesions and background parenchymal enhancement

In ultrafast breast DCE-MRI, Gadavist demonstrated stronger early enhancement kinetics, whereas Dotarem provided improved tumor-to-BPE contrast and higher sensitivity for select kinetic parameters. These findings underscore the importance of tailoring contrast agent selection to specific diagnostic goals.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2025-10-29
DOI
https://doi.org/10.21037/qims-2025-1111
Primary Topic
Lanthanide and Transition Metal Complexes
Type
article
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article

Ultrafast breast DCE-MRI: comparative analysis of semi-quantitative and pharmacokinetic parameters with gadoterate meglumine versus gadobutrol in malignant lesions and background parenchymal enhancement

Hiroyuki Abé, Saengsiri Chumsaengsri, Kirti Kulkarni, Zhen Ren et al.
Quantitative Imaging in Medicine and Surgery
Lanthanide and Transition Metal Complexes
article

Ultrafast breast DCE-MRI: comparative analysis of semi-quantitative and pharmacokinetic parameters with gadoterate meglumine versus gadobutrol in malignant lesions and background parenchymal enhancement

Hiroyuki Abé, Saengsiri Chumsaengsri, Kirti Kulkarni, Zhen Ren, Gregory S. Karczmar
article en

Abstract

In ultrafast breast DCE-MRI, Gadavist demonstrated stronger early enhancement kinetics, whereas Dotarem provided improved tumor-to-BPE contrast and higher sensitivity for select kinetic parameters. These findings underscore the importance of tailoring contrast agent selection to specific diagnostic goals.

Quantitative Imaging in Medicine and SurgeryVol. 15(11)
University of Chicago (US), Chulabhorn Hospital (TH)
Openalex Percentile: Top 75%
Lanthanide and Transition Metal Complexes
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