Effect and Mechanism of Apoptotic Bodies from Inflammatory Periodontal Ligament Stem Cells on Macrophage M1 Polarisation
PD-ABs are a potential pathogenesis of periodontitis that induces M1 polarisation via the OSM/JAK2/STAT3 axis. These findings provide new insights into the potential pathogenesis and therapeutic strategies for periodontitis, offering a novel approach to modulate macrophage polarisation and inflammation.
Authors
- Jinlong Weng
- Janak Lal. Pathak (ORCID: https://orcid.org/0000-0003-2576-443X)
- Guanxiong Zhu
- Zeyu Zhang (ORCID: https://orcid.org/0000-0002-9095-2667)
- Zidan Xu
- Hongru Zhang (ORCID: https://orcid.org/0000-0002-2921-1413)
- Liting Zeng
- Lina Yu (ORCID: https://orcid.org/0009-0003-2719-5004)
- Junyi Xia (ORCID: https://orcid.org/0009-0004-2431-9160)
- Jingyuan Wang
Institutions
- Stomatology Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1016/j.identj.2025.103981
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00