Cross reactivity within pneumococcal serogroups 6 and 15 following adult vaccination with pneumococcal conjugate vaccine V116
V116-induced antibodies demonstrate cross-reactivity to serotypes 6C and 15B, suggesting protective immune responses may be raised against these non-vaccine serotypes.
Authors
- Heather Platt (ORCID: https://orcid.org/0000-0002-0910-6077)
- Ulrike K. Buchwald (ORCID: https://orcid.org/0000-0002-6671-0115)
- Katrina M. Nolan (ORCID: https://orcid.org/0000-0001-5030-7930)
- Wen‐Yu Hu (ORCID: https://orcid.org/0000-0001-5244-2458)
- Weifeng Xu (ORCID: https://orcid.org/0000-0001-7598-1489)
- Timothy J. Chapman (ORCID: https://orcid.org/0000-0002-2337-2136)
- Jianing Li (ORCID: https://orcid.org/0000-0002-5892-9934)
- Jonathan Hartzel
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1038/s43856-025-01106-z
- Citations
- 2
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71