Detection of Acute Tropical Fever Pathogens via Multiplex Polymerase Chain Reaction: A Cross-Sectional Study to Guide Appropriate Antimicrobial Use in Communities

While multiplex PCR demonstrates high accuracy in detecting malaria, its limited sensitivity for dengue and typhoid highlights the need for more advanced molecular assays. Developing rapid and reliable diagnostic tests is essential to enable targeted treatment and promote antimicrobial stewardship within the community.

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Publication Details

Journal
Cureus
Published
2025-10-29
DOI
https://doi.org/10.7759/cureus.95654
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
0.00
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article

Detection of Acute Tropical Fever Pathogens via Multiplex Polymerase Chain Reaction: A Cross-Sectional Study to Guide Appropriate Antimicrobial Use in Communities

Seema Irfan, Farah Naz Qamar, Rasha F. Ahmed, Afia Zafar et al.
Cureus
Malaria Research and Control
article

Detection of Acute Tropical Fever Pathogens via Multiplex Polymerase Chain Reaction: A Cross-Sectional Study to Guide Appropriate Antimicrobial Use in Communities

Seema Irfan, Farah Naz Qamar, Rasha F. Ahmed, Afia Zafar, Najia Karim Ghanchi, Ammarah Baig
article en

Abstract

While multiplex PCR demonstrates high accuracy in detecting malaria, its limited sensitivity for dengue and typhoid highlights the need for more advanced molecular assays. Developing rapid and reliable diagnostic tests is essential to enable targeted treatment and promote antimicrobial stewardship within the community.

CureusVol. 17(10)
Aga Khan University Hospital (PK)
Openalex Percentile: Top 59%
Malaria Research and Control
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