Protective Effects of Irisin Against LPS-Induced Intestinal Injury and Its Influence on Gut Microbiota in Septic Mice
Irisin effectively treats septic acute intestinal injury by reducing apoptosis and inflammation, with the intestinal microbiota likely playing a crucial role. This finding offers a novel approach to clinical management of sepsis.
Authors
- Buqu Hu (ORCID: https://orcid.org/0000-0001-7233-987X)
- Kwee Yong (ORCID: https://orcid.org/0000-0002-6487-276X)
- Jun Zhou (ORCID: https://orcid.org/0000-0002-0716-3967)
- Ning Yang (ORCID: https://orcid.org/0000-0001-5772-3320)
- Miao Liu (ORCID: https://orcid.org/0000-0002-7975-6702)
- Ye Chen (ORCID: https://orcid.org/0000-0002-4511-9262)
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/jir.s542608
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00