Association between long-term stimulant treatment and the functional brain response to methylphenidate in adolescents and adults with attention-deficit/hyperactivity disorder

The identified age-dependent associations may potentially be mediated by changes in dopamine- and noradrenaline-related functioning, and may hold predictive value for extent of stimulant medication use after ADHD diagnosis in children and adolescents.

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Publication Details

Journal
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Published
2025-10-29
DOI
https://doi.org/10.1016/j.pnpbp.2025.111545
Primary Topic
Attention Deficit Hyperactivity Disorder
Type
article
Field-Weighted Citation Impact
0.00

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article

Association between long-term stimulant treatment and the functional brain response to methylphenidate in adolescents and adults with attention-deficit/hyperactivity disorder

Hilde M. Geurts, Anouk Schrantee, Liesbeth Reneman, Zarah van der Pal et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Attention Deficit Hyperactivity Disorder
article

Association between long-term stimulant treatment and the functional brain response to methylphenidate in adolescents and adults with attention-deficit/hyperactivity disorder

Hilde M. Geurts, Anouk Schrantee, Liesbeth Reneman, Zarah van der Pal, Henk J. M. M. Mutsaerts, Marco Bottelier, Antonia Kaiser
article en

Abstract

The identified age-dependent associations may potentially be mediated by changes in dopamine- and noradrenaline-related functioning, and may hold predictive value for extent of stimulant medication use after ADHD diagnosis in children and adolescents.

Progress in Neuro-Psychopharmacology and Biological PsychiatryVol. 143
Amsterdam Neuroscience (NL), Accare (NL), Centre d'Imagerie BioMedicale (CH), Amsterdam University Medical Centers (NL), École Polytechnique Fédérale de Lausanne (CH), Amsterdam University of Applied Sciences (NL), Vrije Universiteit Amsterdam (NL), University of Amsterdam (NL)
Universiteit van Amsterdam
Openalex Percentile: Top 63%
Attention Deficit Hyperactivity Disorder
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