Neurofunctional phenotyping to investigate the role of the orexin system at the intersection of opioid use disorder and insomnia: a protocol for a randomised, placebo-controlled clinical trial of lemborexant in patients with insomnia receiving bupren

Authors

Katina Swan (ORCID: https://orcid.org/0000-0003-4530-5548)
A Green
Caitlin E. Martin (ORCID: https://orcid.org/0000-0001-5560-458X)
F. Gerard Moeller (ORCID: https://orcid.org/0000-0003-3683-1407)
Maha Alattar
Lori Keyser‐Marcus (ORCID: https://orcid.org/0000-0001-6014-2500)
Madison M. Marcus (ORCID: https://orcid.org/0000-0002-8403-5395)
Roy Sabo (ORCID: https://orcid.org/0000-0001-9159-4876)
Shanshan Chen (ORCID: https://orcid.org/0009-0006-1774-5836)
Tiffany Pignatello
Joyce Ruddley

Institutions

Virginia Commonwealth University (US)

Publication Details

Journal: BMJ Open
Published: 2025-10-01
DOI: https://doi.org/10.1136/bmjopen-2025-108613
Primary Topic: Sleep and Wakefulness Research
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Georgia Clinical and Translational Science Alliance
National Institutes of Health
National Institute on Drug Abuse
National Center for Advancing Translational Sciences

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article

Neurofunctional phenotyping to investigate the role of the orexin system at the intersection of opioid use disorder and insomnia: a protocol for a randomised, placebo-controlled clinical trial of lemborexant in patients with insomnia receiving bupren

Katina Swan, A Green, Caitlin E. Martin, F. Gerard Moeller et al.

Oct 1, 2025

BMJ Open

Sleep and Wakefulness Research

article

Neurofunctional phenotyping to investigate the role of the orexin system at the intersection of opioid use disorder and insomnia: a protocol for a randomised, placebo-controlled clinical trial of lemborexant in patients with insomnia receiving bupren

Katina Swan, A Green, Caitlin E. Martin, F. Gerard Moeller, Maha Alattar, Lori Keyser‐Marcus, Madison M. Marcus, Roy Sabo, Shanshan Chen, Tiffany Pignatello, Joyce Ruddley

October 1, 2025article en

Abstract

No abstract available for this paper.

BMJ OpenVol. 15(10)

Virginia Commonwealth University (US)

Georgia Clinical and Translational Science Alliance, National Institutes of Health, National Institute on Drug Abuse, National Center for Advancing Translational Sciences

Openalex Percentile: Top 69%

Sleep and Wakefulness Research

DOI Open Access PDF OpenAlex

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Neurofunctional phenotyping to investigate the role of the orexin system at the intersection of opioid use disorder and insomnia: a protocol for a randomised, placebo-controlled clinical trial of lemborexant in patients with insomnia receiving bupren — Katina Swan, A Green, et al. · BMJ Open (2025) | TGRS Research Map | TGRS