Epigenetic mediation may explain intergenerational associations between maternal obesogenic lifestyle and children’s birth weight: findings from the NorthPop prospective birth cohort
Our findings support the hypothesis that neonatal health effects related to maternal lifestyle may be partly mediated by epigenetic alterations. Findings also suggest the possible involvement of multiple DNA methylation sites via various mediatory pathways.
Authors
- Stina Bodén (ORCID: https://orcid.org/0000-0002-8958-975X)
- Christina E. West (ORCID: https://orcid.org/0000-0001-9599-2580)
- Patrik Rydén (ORCID: https://orcid.org/0000-0002-0577-123X)
- Magnus Domellöf (ORCID: https://orcid.org/0000-0002-0726-7029)
- Marie‐Therese Vinnars (ORCID: https://orcid.org/0000-0002-4673-0960)
- Kushan De Silva (ORCID: https://orcid.org/0000-0003-0301-0805)
- Sophia Harlid (ORCID: https://orcid.org/0000-0001-8540-6891)
- Richard Lundberg-Ulfsdotter (ORCID: https://orcid.org/0000-0003-0399-4189)
Institutions
- Helmholtz Zentrum München (DE)
- Umeå University (SE)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s13148-025-02001-z
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Västerbotten Läns Landsting
- Knut och Alice Wallenbergs Stiftelse
- Vetenskapsrådet
- Science for Life Laboratory