Identification and experimental verification of necroptosis-related prognostic gene signature and characterization of tumor immune infiltration in lung squamous cell carcinoma
A three-gene NRG signature was identified as a prognostic marker in LUSC. These genes appear to influence disease progression and the immune microenvironment, highlighting their potential as therapeutic targets and as a foundation for further investigation.
Authors
- Song Wen (ORCID: https://orcid.org/0000-0001-6173-0507)
- Kai Sun (ORCID: https://orcid.org/0000-0001-9619-9007)
- Fangfang Xie (ORCID: https://orcid.org/0000-0003-2668-460X)
- Kongjia Wang (ORCID: https://orcid.org/0009-0002-0995-409X)
- Juan-juan Hong
- Qinghua Pan (ORCID: https://orcid.org/0000-0002-0767-4089)
- Yulang Fei
Institutions
- Liuzhou Maternal and Child Health Hospital (CN)
- Liuzhou General Hospital (CN)
- Ganzhou People's Hospital (CN)
- Gannan Medical University (CN)
- Guangxi Zhuang Autonomous Region Brain Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Nanyang Medical College (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-10-29
- DOI
- https://doi.org/10.7717/peerj.20260
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00