Muscle energetics and the cardiovascular response to isometric exercise and post-exercise circulatory occlusion following exercise-induced muscle damage: insights from multiparametric MRI

Our multi-parametric MRI approach provides new insights into the local effects of muscle damage on energy metabolism, oxygenation, and Na<sup>+</sup>. Despite these local metabolic and microvascular disturbances, systemic cardiovascular responses, as indicated by MAP and HR, remained unchanged. These new findings suggest a dissociation between muscle metabolites, oxygenation, and the cardiovascular response to exercise and PECO 48 h after damaging exercise.

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Publication Details

Journal
Frontiers in Physiology
Published
2025-10-29
DOI
https://doi.org/10.3389/fphys.2025.1636964
Primary Topic
Advanced MRI Techniques and Applications
Type
article
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article

Muscle energetics and the cardiovascular response to isometric exercise and post-exercise circulatory occlusion following exercise-induced muscle damage: insights from multiparametric MRI

Jean‐Christophe Lagacé, Fabio Zambolin, Jamie S. McPhee, Susan Pinner et al.
Frontiers in Physiology
Advanced MRI Techniques and Applications
article

Muscle energetics and the cardiovascular response to isometric exercise and post-exercise circulatory occlusion following exercise-induced muscle damage: insights from multiparametric MRI

Jean‐Christophe Lagacé, Fabio Zambolin, Jamie S. McPhee, Susan Pinner, Aneurin J. Kennerley, Fiona E. Smith, James McStravick
article en

Abstract

Our multi-parametric MRI approach provides new insights into the local effects of muscle damage on energy metabolism, oxygenation, and Na<sup>+</sup>. Despite these local metabolic and microvascular disturbances, systemic cardiovascular responses, as indicated by MAP and HR, remained unchanged. These new findings suggest a dissociation between muscle metabolites, oxygenation, and the cardiovascular response to exercise and PECO 48 h after damaging exercise.

Frontiers in PhysiologyVol. 16
Manchester Metropolitan University (GB), Université de Sherbrooke (CA), Health and Social Services Centre University Institute of Geriatrics of Sherbrooke (CA)
Openalex Percentile: Top 54%
Advanced MRI Techniques and Applications
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