Relationship between Ki-67 and P53 immunohistochemical expression and osteosarcoma chemotherapy sensitivity and long-term prognosis

Lower levels of select inflammatory markers, IDH1 mutation status, LDH, and Ki-67 expression were independently associated with increased chemotherapy sensitivity and improved prognosis in osteosarcoma. These biomarkers may aid in risk stratification and therapeutic decision-making for affected patients.

Authors

Institutions

Publication Details

Journal
American Journal of Translational Research
Published
2025-01-01
DOI
https://doi.org/10.62347/ktyo7957
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Relationship between Ki-67 and P53 immunohistochemical expression and osteosarcoma chemotherapy sensitivity and long-term prognosis

Gu Z
American Journal of Translational Research
Sarcoma Diagnosis and Treatment
article

Relationship between Ki-67 and P53 immunohistochemical expression and osteosarcoma chemotherapy sensitivity and long-term prognosis

Gu Z
article en

Abstract

Lower levels of select inflammatory markers, IDH1 mutation status, LDH, and Ki-67 expression were independently associated with increased chemotherapy sensitivity and improved prognosis in osteosarcoma. These biomarkers may aid in risk stratification and therapeutic decision-making for affected patients.

American Journal of Translational ResearchVol. 17(10)
Ningbo University (CN), Ningbo Center for Disease Control and Prevention (CN), Ningbo No. 2 Hospital (CN), Ningbo College of Health Sciences (CN), Ningbo No.6 Hospital (CN)
Openalex Percentile: Top 55%
Sarcoma Diagnosis and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.