Astrocyte Interactions With Ti <sub>3</sub> C <sub>2</sub> T <i> <sub>x</sub> </i> MXene Flakes: Insights Into Viability, Morphology, and Functionality (Adv. Mater. Interfaces 20/2025)
Ti3C2Tx MXene on Astrocytes This image shows Ti3C2Tx MXene flakes on the astrocyte membrane. Ti3C2Tx MXene is a two-dimensional nanomaterial with promising properties for application in bioelectronics. In this first systematic evaluation of astrocyte–MXene interactions, scanning electron microscopy reveals Ti3C2Tx adhering to astrocytes without causing any evident alteration of the membrane. Alongside viability, morphology, and calcium imaging assays, these findings establish for the first time the biocompatibility of Ti3C2Tx MXene with astrocytes. More details can be found in the Research Article by Flavia Vitale, D. Kacy Cullen, and co-workers (DOI: 10.1002/admi.202500261).
Authors
- Yihan Xie (ORCID: https://orcid.org/0009-0002-3084-3204)
- Flavia Vitale (ORCID: https://orcid.org/0000-0001-8644-550X)
- Raghav Garg (ORCID: https://orcid.org/0000-0002-3501-6892)
- John C. O’Donnell (ORCID: https://orcid.org/0000-0001-8101-3783)
- Cybelle Smith (ORCID: https://orcid.org/0000-0002-8237-3761)
- Daniel Kacy Cullen (ORCID: https://orcid.org/0000-0002-5355-5216)
- Elizabeth N. Krizman (ORCID: https://orcid.org/0000-0001-8529-587X)
- Dimitris Boufidis (ORCID: https://orcid.org/0000-0001-8901-7957)
Institutions
- Translational Therapeutics (United States) (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Advanced Materials Interfaces
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/admi.70207
- Primary Topic
- MXene and MAX Phase Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00