Identification and validation of mitochondrial-related genes in intestinal ischemia-reperfusion injury based on WGCNA and machine learning
Pdk4, Yrdc, Bcl2l11, and Pmaip1 have been identified as hub genes closely associated with mitochondrial function in eraly II/R injury, thereby providing a theoretical basis for the diagnosis and treatment of eraly II/R injury.
Authors
- Jie Huang (ORCID: https://orcid.org/0000-0002-6657-8740)
- Jiahui Wang (ORCID: https://orcid.org/0000-0001-5681-5055)
- Yichen Hu (ORCID: https://orcid.org/0000-0002-0720-583X)
- Wenliang Li
- YuanPei Zhao
- K. Shi
- Hongyuan Liu (ORCID: https://orcid.org/0000-0002-5437-4695)
- Weiming Li (ORCID: https://orcid.org/0000-0001-9220-514X)
- Xiao‐Li Min (ORCID: https://orcid.org/0009-0009-1025-8041)
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fmolb.2025.1691749
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Kunming Medical University