Haemophagocytic lymphohistiocytosis in critically ill adults: a single-centre retrospective ICU cohort study

HLH in adult ICUs carries high mortality and demands extensive organ support. Existing diagnostic scores provide limited bedside guidance, highlighting the need for ICU-specific validation and improved prognostic markers.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-10-29
DOI
https://doi.org/10.3389/fmed.2025.1641659
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Haemophagocytic lymphohistiocytosis in critically ill adults: a single-centre retrospective ICU cohort study

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Frontiers in Medicine
Autoimmune and Inflammatory Disorders Research
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Haemophagocytic lymphohistiocytosis in critically ill adults: a single-centre retrospective ICU cohort study

Hanno Maximilian Witte, Dominic Wichmann, Martin Krusche, Stefan Kluge, Axel Nierhaus, Kevin Roedl, Markus Haar, Paymon Ahmadi, Alina Stadermann, Joseph Tintelnot, Fabian Gleibs
article en

Abstract

HLH in adult ICUs carries high mortality and demands extensive organ support. Existing diagnostic scores provide limited bedside guidance, highlighting the need for ICU-specific validation and improved prognostic markers.

Frontiers in MedicineVol. 12
Universität Hamburg (DE), University Medical Center Hamburg-Eppendorf (DE), Bundeswehrkrankenhaus Ulm (DE)
Openalex Percentile: Top 61%
Autoimmune and Inflammatory Disorders Research
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