The impact of the limbal niche interactions on the self-renewal capability of limbal epithelial stem cells
These findings illustrate the potential of utilizing niche-cell-conditioned media and direct contact with FN on the self-renewal of LESCs <i>in vitro</i>. Further research is required to provide a more comprehensive understanding of these effects and to elucidate the underlying mechanisms of action.
Authors
- Jesper Hjortdal (ORCID: https://orcid.org/0000-0002-1309-8006)
- Hiva Alipour (ORCID: https://orcid.org/0000-0002-8500-4208)
- Vladimir Zachar (ORCID: https://orcid.org/0000-0002-5279-2690)
- Qiuyue Peng (ORCID: https://orcid.org/0000-0002-4951-9968)
- Fereshteh Dardmeh (ORCID: https://orcid.org/0000-0002-2034-0147)
- Sara Aghazadeh (ORCID: https://orcid.org/0000-0002-4824-1757)
Institutions
- Aarhus University Hospital (DK)
- Aalborg University (DK)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fcell.2025.1667309
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Aalborg Universitet