Psychological side effects of antipsychotic medication after remission from first-episode psychosis: a HAMLETT ecological momentary assessment study

Higher antipsychotic dosage and high-affinity D<sub>2</sub> antagonists were associated with decreased positive affect after remission from FEP, which may partly drive the frequently reported blunting of emotional experience.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s003329172510216x
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Psychological side effects of antipsychotic medication after remission from first-episode psychosis: a HAMLETT ecological momentary assessment study

Marieke Begemann, Matej Djordjevic, Machteld Marcelis, Martijn Kikkert et al.
Psychological Medicine
Schizophrenia research and treatment
article

Psychological side effects of antipsychotic medication after remission from first-episode psychosis: a HAMLETT ecological momentary assessment study

Marieke Begemann, Matej Djordjevic, Machteld Marcelis, Martijn Kikkert, Iris E. Sommer, Shiral S. Gangadin, Claudia J.P. Simons, Priscilla P. Oomen, Hannah E. Jongsma, Mark J. Nijland, Wim Veling, Lieuwe de Haan
article en

Abstract

Higher antipsychotic dosage and high-affinity D<sub>2</sub> antagonists were associated with decreased positive affect after remission from FEP, which may partly drive the frequently reported blunting of emotional experience.

Psychological MedicineVol. 55
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), University of Groningen (NL), Maastricht University (NL), National Health Care Institute (NL), Reinier van Arkel (NL), Amsterdam University Medical Centers (NL), Transcultural Mental Health Institute (US)
ZonMw, Universitair Medisch Centrum Groningen
Openalex Percentile: Top 63%
Schizophrenia research and treatment
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Psychological side effects of antipsychotic medication after remission from first-episode psychosis: a HAMLETT ecological momentary assessment study — Marieke Begemann, Matej Djordjevic, et al. · Psychological Medicine (2025) | TGRS Research Map | TGRS