Radiation-induced cavernous malformation within a vestibular schwannoma: A case report

Cavernous malformations are a well-described complication of intracranial radiation; however, have only once previously been described within a vestibular schwannoma following radiotherapy. We report a case of a 78-year-old woman presenting with new hemifacial spasm 16-years following fractionated radiotherapy for a vestibular schwannoma, with imaging suggesting the formation of a cavernous malformation within the tumor. The patient underwent translabyrinthine resection, with final pathology confirming the diagnosis of a cavernous malformation within the vestibular schwannoma. This case highlights the need to maintain a broad differential in patients with new symptoms following radiotherapy for vestibular schwannomas, including hemifacial spasm. Cavernous malformations should be considered among potential radiation-related complications in patients with vestibular schwannoma. <b>Level of Evidence:</b> IV.

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Journal
SAGE Open Medical Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1177/2050313x251390626
Primary Topic
Meningioma and schwannoma management
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article
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article

Radiation-induced cavernous malformation within a vestibular schwannoma: A case report

Sabrina M. Heman-Ackah, Douglas C. Bigelow, Jason A. Brant, Alexandra E. Quimby et al.
SAGE Open Medical Case Reports
Meningioma and schwannoma management
article

Radiation-induced cavernous malformation within a vestibular schwannoma: A case report

Sabrina M. Heman-Ackah, Douglas C. Bigelow, Jason A. Brant, Alexandra E. Quimby, Alex Z. Graboyes, John Y. K. Lee, S Stone
article en

Abstract

Cavernous malformations are a well-described complication of intracranial radiation; however, have only once previously been described within a vestibular schwannoma following radiotherapy. We report a case of a 78-year-old woman presenting with new hemifacial spasm 16-years following fractionated radiotherapy for a vestibular schwannoma, with imaging suggesting the formation of a cavernous malformation within the tumor. The patient underwent translabyrinthine resection, with final pathology confirming the diagnosis of a cavernous malformation within the vestibular schwannoma. This case highlights the need to maintain a broad differential in patients with new symptoms following radiotherapy for vestibular schwannomas, including hemifacial spasm. Cavernous malformations should be considered among potential radiation-related complications in patients with vestibular schwannoma. <b>Level of Evidence:</b> IV.

SAGE Open Medical Case ReportsVol. 13
Dalhousie University (CA), University of Wisconsin–Madison (US), University of Michigan (US), Michigan Medicine (US), William S. Middleton Memorial Veterans Hospital (US), Wisconsin Division of Public Health (US), University of Pennsylvania (US)
Openalex Percentile: Top 58%
Meningioma and schwannoma management
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Radiation-induced cavernous malformation within a vestibular schwannoma: A case report — Sabrina M. Heman-Ackah, Douglas C. Bigelow, et al. · SAGE Open Medical Case Reports (2025) | TGRS Research Map | TGRS