Effect of Vosoritide Therapy on IGF-I and Endogenous C-Type Natriuretic Peptide in Hypochondroplasia
In children with HCH, IGF-1 levels are reduced and NTproCNP levels are elevated at baseline. A correlation between changes in these levels during treatment suggests a possible interaction between IGF-1 and CNP signaling.
Authors
- Timothy C. R. Prickett (ORCID: https://orcid.org/0000-0002-9684-5096)
- Andrew Dauber (ORCID: https://orcid.org/0000-0003-4890-0262)
- Despoina Galetaki (ORCID: https://orcid.org/0000-0002-8943-0386)
- Eric A. Espiner (ORCID: https://orcid.org/0000-0002-3318-3929)
- Roopa Kanakatti Shankar (ORCID: https://orcid.org/0000-0001-9653-8865)
- Niusha Shafaei
- Raheem Seaforth
- Anqing Zhang (ORCID: https://orcid.org/0000-0003-3043-8014)
- Kimberly Pitner
Institutions
- Children's National (US)
- George Washington University (US)
- University of Otago (NZ)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1210/clinem/dgaf591
- Primary Topic
- Connective tissue disorders research
- Type
- article
- Field-Weighted Citation Impact
- 0.00