Radiographic Severity and Clinical Implications of Knee Osteoarthritis in Adults Under 55: Incidence and Insight Into Potential Candidates for Geniculate Artery Embolisation

Over half of symptomatic outpatients under 55 had definite radiographic OA, and one-third had moderate-to-severe disease, highlighting a substantial disease burden in "younger" adults. Given joint-replacement deferral in this age group, GAE warrants evaluation within research pathways for persistent, treatment-refractory pain. The National Institute for Health and Care Excellence (NICE) currently recommends GAE only in research settings.