Iridium-catalysed direct C–H alkylation of sugar derivatives with alkenes
The iridium-catalysed direct C-H alkylation of glycals with simple terminal alkenes was enabled by an amide directing group and sterically tuned diphosphine ligands. The reaction proceeded with high linear selectivity and broad substrate scope, tolerating styrene derivatives, vinylsilanes, acrylates, and several glycal frameworks including glucal, galactal, and rhamnal.
Authors
- Takahiro Nishimura (ORCID: https://orcid.org/0000-0002-7032-8613)
- Katsumasa Tanaka (ORCID: https://orcid.org/0000-0001-9601-6442)
- Masahiro Tatara
Institutions
- Osaka Metropolitan University (JP)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc05042a
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.94