Association between hyperglycaemia, diabetes complications and development of fibrotic conditions among people living with type 1 and type 2 diabetes in England: a retrospective cohort study using UK Clinical Resource Datalink Aurum and Hospital Epis
Within the T1DM population, no consistent association between diabetes status and all fibrotic diseases was observed. More research is required to understand whether the association between diabetes complications and fibrotic diseases is due to shared risk factors or whether glycaemia in T2DM may be influenced by fibrotic pathology.
Authors
- Gísli Jenkins (ORCID: https://orcid.org/0000-0002-7929-2119)
- Sarah Cook (ORCID: https://orcid.org/0000-0003-1250-2967)
- Samuel Moss (ORCID: https://orcid.org/0000-0002-1872-9110)
- Iain D. Stewart (ORCID: https://orcid.org/0000-0002-1340-2688)
- Georgie May Massen (ORCID: https://orcid.org/0000-0003-4355-6546)
- Jennifer Kathleen Quint (ORCID: https://orcid.org/0000-0003-0149-4869)
- Louise V. Wain (ORCID: https://orcid.org/0000-0003-4951-1867)
- Richard J. Allen (ORCID: https://orcid.org/0000-0002-8450-3056)
- Daniel L. Morganstein (ORCID: https://orcid.org/0000-0003-1565-8617)
- Rachel C. Chambers (ORCID: https://orcid.org/0000-0003-1370-9417)
- Nick S. Oliver (ORCID: https://orcid.org/0000-0003-3525-3633)
Institutions
- University of Leicester (GB)
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Royal Marsden Hospital (GB)
- NIHR Leicester Biomedical Research Centre (GB)
- University College London (GB)
- Imperial College London (GB)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-103426
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- UK Research and Innovation
- Medical Research Council