Surgical management as initial treatment for cutaneous leishmaniasis: An example using a case of Leishmania panamensis infection

Cutaneous leishmaniasis is a parasitic infection caused by intracellular protozoa of the genus Leishmania<sup>1</sup>. It is endemic to over 70 countries, with more than 30 sandfly species identified as vectors<sup>1</sup>. Leishmania panamensis is a major cause of disease in Central and South America<sup>1</sup>. The cutaneous form typically presents as chronic granulomatous papules or plaques on the face, arms, or legs, which may be nodular or ulcerative and can persist for years, often leaving disfiguring scars<sup>1</sup>.Treatment generally involves systemic antimonials such as sodium stibogluconate or alternative agents including pentamidine, amphotericin B, and paromomycin<sup>2-4</sup>. Surgical management is typically reserved for cosmetically sensitive areas or refractory lesions<sup>5-6</sup>. We present a case of L. panamensis infection with a large ulcerated plaque that progressed despite initial surgical intervention, ultimately requiring systemic antimicrobial therapy<sup>7</sup>.

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Journal
IDCases
Published
2025-01-01
DOI
https://doi.org/10.1016/j.idcr.2025.e02401
Primary Topic
Research on Leishmaniasis Studies
Type
article
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article

Surgical management as initial treatment for cutaneous leishmaniasis: An example using a case of Leishmania panamensis infection

Drew A. Emge, Peter Chow, Kevin Varghese, Develyn Vetos et al.
IDCases
Research on Leishmaniasis Studies
article

Surgical management as initial treatment for cutaneous leishmaniasis: An example using a case of Leishmania panamensis infection

Drew A. Emge, Peter Chow, Kevin Varghese, Develyn Vetos, Ethan Fluck
article en

Abstract

Cutaneous leishmaniasis is a parasitic infection caused by intracellular protozoa of the genus Leishmania<sup>1</sup>. It is endemic to over 70 countries, with more than 30 sandfly species identified as vectors<sup>1</sup>. Leishmania panamensis is a major cause of disease in Central and South America<sup>1</sup>. The cutaneous form typically presents as chronic granulomatous papules or plaques on the face, arms, or legs, which may be nodular or ulcerative and can persist for years, often leaving disfiguring scars<sup>1</sup>.Treatment generally involves systemic antimonials such as sodium stibogluconate or alternative agents including pentamidine, amphotericin B, and paromomycin<sup>2-4</sup>. Surgical management is typically reserved for cosmetically sensitive areas or refractory lesions<sup>5-6</sup>. We present a case of L. panamensis infection with a large ulcerated plaque that progressed despite initial surgical intervention, ultimately requiring systemic antimicrobial therapy<sup>7</sup>.

IDCasesVol. 42
University of Kansas Medical Center (US)
Openalex Percentile: Top 59%
Research on Leishmaniasis Studies
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