Rational design of promoter editing confers multipathogen resistance in rice
Our study has generated an edited promoter of RBL1 that confers multipathogen resistance with no yield penalty. Our study demonstrates a framework for predictable promoter engineering in balancing agronomic traits, especially through optimizing LMMs for crop improvement.
Authors
- Gan Sha (ORCID: https://orcid.org/0009-0008-1966-8656)
- Qiping Sun (ORCID: https://orcid.org/0009-0003-9832-8994)
- Kabin Xie (ORCID: https://orcid.org/0000-0003-0643-2456)
- Guotian Li (ORCID: https://orcid.org/0000-0001-6780-7085)
- Peng Sun (ORCID: https://orcid.org/0000-0001-5746-9684)
- Tom Hsiang (ORCID: https://orcid.org/0000-0002-9549-1847)
- Anum Bashir
- Yongxin Xiao
- Guang Chen (ORCID: https://orcid.org/0000-0003-3906-9331)
- Yin Wang (ORCID: https://orcid.org/0000-0001-6729-7230)
- Lin Lin (ORCID: https://orcid.org/0000-0003-2084-8183)
- Qiang Li (ORCID: https://orcid.org/0000-0002-1686-9005)
- Ling Li (ORCID: https://orcid.org/0000-0002-0087-3034)
- Weibo Xie (ORCID: https://orcid.org/0000-0002-2768-3572)
- Lei Yang (ORCID: https://orcid.org/0000-0002-8567-018X)
- Chen Tian (ORCID: https://orcid.org/0000-0002-4508-8080)
- Xinyu Han (ORCID: https://orcid.org/0009-0002-0831-6774)
- Zhenhua Guo (ORCID: https://orcid.org/0000-0002-6745-2322)
- Fengdie Xia
- Xiaojing Kong
Institutions
- Huazhong Agricultural University (CN)
- University of Guelph (CA)
Publication Details
- Journal
- Genome biology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s13059-025-03841-x
- Citations
- 4
- Primary Topic
- Genetic Mapping and Diversity in Plants and Animals
- Type
- article
- Field-Weighted Citation Impact
- 7.27
Funders
- National Natural Science Foundation of China
- Huazhong Agricultural University
- Fundamental Research Funds for the Central Universities