Proteome-wide and network pharmacology integration identifies sunitinib as a potential therapeutic for type 2 diabetes targets

This study identifies novel T2D therapeutic targets and highlights sunitinib as a promising candidate. Future work should validate these findings and assess sunitinib's efficacy in clinical trials.

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Publication Details

Journal
Therapeutic Advances in Endocrinology and Metabolism
Published
2025-10-01
DOI
https://doi.org/10.1177/20420188251376325
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Proteome-wide and network pharmacology integration identifies sunitinib as a potential therapeutic for type 2 diabetes targets

Yuanyuan Kong, Hong Zhu, Huixin Tong, Hao Yu et al.
Therapeutic Advances in Endocrinology and Metabolism
PI3K/AKT/mTOR signaling in cancer
article

Proteome-wide and network pharmacology integration identifies sunitinib as a potential therapeutic for type 2 diabetes targets

Yuanyuan Kong, Hong Zhu, Huixin Tong, Hao Yu, Liang Shi
article en

Abstract

This study identifies novel T2D therapeutic targets and highlights sunitinib as a promising candidate. Future work should validate these findings and assess sunitinib's efficacy in clinical trials.

Therapeutic Advances in Endocrinology and MetabolismVol. 16
General Hospital of Shenyang Military Region (CN)
Openalex Percentile: Top 72%
PI3K/AKT/mTOR signaling in cancer
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