The relationship between frailty and multimorbidity in Chinese older adults: the chain mediating effects of sleep quality and anxiety

Frailty was positively associated with multimorbidity, and sleep quality and anxiety were important mediators of the association between frailty and multimorbidity. Addressing frailty, enhancing sleep quality, and promoting a positive mood may help reduce multimorbidity and enhance the overall well-being of elderly individuals. This study could potentially contribute to the development of more effective strategies to prevent multimorbidity.

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Publication Details

Journal
BMC Geriatrics
Published
2025-10-27
DOI
https://doi.org/10.1186/s12877-025-06490-8
Primary Topic
Chronic Disease Management Strategies
Type
article
Field-Weighted Citation Impact
0.00

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article

The relationship between frailty and multimorbidity in Chinese older adults: the chain mediating effects of sleep quality and anxiety

Guoxian Li, Liang Zhou, Yueping Shen, Ze Ma et al.
BMC Geriatrics
Chronic Disease Management Strategies
article

The relationship between frailty and multimorbidity in Chinese older adults: the chain mediating effects of sleep quality and anxiety

Guoxian Li, Liang Zhou, Yueping Shen, Ze Ma, Mengtong Sun, Jianing Li, Qiang Han, Miao Jiang, Ziqing Sun, Yujie Shi, Hanqing Zhao, Yu Wang, Zexin Lou
article en

Abstract

Frailty was positively associated with multimorbidity, and sleep quality and anxiety were important mediators of the association between frailty and multimorbidity. Addressing frailty, enhancing sleep quality, and promoting a positive mood may help reduce multimorbidity and enhance the overall well-being of elderly individuals. This study could potentially contribute to the development of more effective strategies to prevent multimorbidity.

BMC GeriatricsVol. 25(1)
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN), Liuyang City Maternal and Child Health Hospital (CN), First Affiliated Hospital of Soochow University (CN)
National Natural Science Foundation of China, Soochow University
Openalex Percentile: Top 58%
Chronic Disease Management Strategies
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The relationship between frailty and multimorbidity in Chinese older adults: the chain mediating effects of sleep quality and anxiety — Guoxian Li, Liang Zhou, et al. · BMC Geriatrics (2025) | TGRS Research Map | TGRS