The role of baseline and persistent depression in adjuvant cancer therapy: impact on toxicity and quality of life
Both baseline depression and functional impairment (ECOG) are independent predictors of depressive symptoms during adjuvant therapy. Persistent depression is significantly associated with increased treatment toxicity and poorer QoL in patients with early-stage resected cancer, highlighting the need for routine screening and early psychological intervention during adjuvant treatment.
Authors
- Juana María Cano-Cano
- Caterina Calderón (ORCID: https://orcid.org/0000-0002-6956-9321)
- Berta Obispo (ORCID: https://orcid.org/0000-0003-1214-6595)
- Alberto Carmona‐Bayonas (ORCID: https://orcid.org/0000-0002-1930-9660)
- Paula Jiménez‐Fonseca (ORCID: https://orcid.org/0000-0003-4592-3813)
- Ismael Ghanem (ORCID: https://orcid.org/0000-0002-1859-0737)
Institutions
- Hospital Universitario La Paz (ES)
- Hospital General Universitario Morales Meseguer (ES)
- Hospital General Universitario de Ciudad Real (ES)
- Hospital Universitario Central de Asturias (ES)
- Hospital Universitario Infanta Leonor (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- International Journal of Clinical and Health Psychology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.ijchp.2025.100640
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sociedad Española de Oncología Médica