Survival outcomes associated with antidepressant use in glioblastoma: a cohort study
Antidepressant therapy is associated with worse survival in patients with glioblastoma after adjusting for known factors with relevance to survival. Clinicians should consider the risks and benefits of prescribing antidepressants in patients with glioblastoma. Further evidence is necessary to better understand the impact of antidepressant therapy in glioblastoma survival.
Authors
- Travis J. Atchley (ORCID: https://orcid.org/0000-0002-8085-6911)
- Dagoberto Estévez-Ordoñez (ORCID: https://orcid.org/0000-0002-8876-1044)
- James M. Markert (ORCID: https://orcid.org/0000-0001-7457-7329)
- Burt Nabors (ORCID: https://orcid.org/0000-0001-5926-2230)
- Mohammad Hamo
- Yifei Sun (ORCID: https://orcid.org/0009-0001-5698-004X)
Institutions
- University of Alabama at Birmingham (US)
- Jackson Health System (US)
Publication Details
- Journal
- Journal of Neuro-Oncology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s11060-025-05288-3
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00