Deciphering the causal relationships between plasma metabolites, peripheral cells, inflammatory factors and DLBCL for discovering novel therapeutic targets
This study revealed a significant causal link between plasma metabolites, peripheral cells, inflammatory factors and DLBCL. It remarkably enhances our understanding of the interplay between immune responses, metabolites and DLBCL risk, providing insights into the development of therapeutic strategies from the metabolite-immune axis alternation perspectives.
Authors
- Ming Xu (ORCID: https://orcid.org/0000-0001-5803-5642)
- Wenhua Zhu
- Wang Li (ORCID: https://orcid.org/0000-0002-7771-1105)
- Weirong Zhu
- Li Xu (ORCID: https://orcid.org/0000-0003-2878-302X)
- Jiayue Xu (ORCID: https://orcid.org/0000-0002-6064-2182)
- Ming Ruan
- Yanjie Qu
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shanxi Province Hospital of Traditional Chinese Medicine (CN)
- The First People's Hospital of Guiyang (CN)
- Shanghai Institute of Hematology (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1007/s12672-025-03688-5
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China