Validation of a Serum-Based Biomarker Signature for Detection of Early-Stage Pancreatic Ductal Adenocarcinoma
These findings indicate that PancreaSure is a high-performing biomarker test to aid in the detection of early-stage PDAC. Overall, this work represents an important step toward improving early-stage diagnostic success.
Authors
- Thomas Charles King (ORCID: https://orcid.org/0009-0006-8581-5824)
- George R. DeMuth (ORCID: https://orcid.org/0000-0002-9249-9843)
- Aimee L. Lucas (ORCID: https://orcid.org/0000-0003-0341-4826)
- Diane M. Simeone (ORCID: https://orcid.org/0000-0001-5142-3087)
- George Zogopoulos (ORCID: https://orcid.org/0000-0002-0482-7086)
- Jessica N. Everett (ORCID: https://orcid.org/0000-0002-4894-8891)
- Fay Kastrinos (ORCID: https://orcid.org/0000-0003-2518-0100)
- Bryson W. Katona (ORCID: https://orcid.org/0000-0001-8186-9119)
- Eli Marie Grindedal (ORCID: https://orcid.org/0000-0002-8198-1706)
- Randall E. Brand (ORCID: https://orcid.org/0000-0002-4136-3313)
- Natasha Kureshi
- Salvatore Paiella (ORCID: https://orcid.org/0000-0001-6893-8618)
- Jose G Trevino
- Sonia S. Kupfer (ORCID: https://orcid.org/0000-0003-4857-2289)
- Erkut Borazanci (ORCID: https://orcid.org/0000-0001-5136-5462)
- Raymond Wadlow (ORCID: https://orcid.org/0000-0003-1959-5406)
- Rosalie C. Sears (ORCID: https://orcid.org/0000-0003-1558-2413)
- Walter G. Park (ORCID: https://orcid.org/0000-0001-8187-4188)
- Norma Alonzo Palma (ORCID: https://orcid.org/0000-0001-6900-0533)
- Ora Gordon
- Lisa Ford
Institutions
- University of Verona (IT)
- Oslo University Hospital (NO)
- Mount Sinai Hospital (US)
- University of San Diego (US)
- Oregon Health & Science University (US)
- Virginia Commonwealth University (US)
- Columbia University Irving Medical Center (US)
- North Carolina Institute of Medicine (US)
- Inova Fairfax Hospital (US)
- UC San Diego Health System (US)
- McGill University Health Centre (CA)
- University of Chicago (US)
- Mount Sinai Hospital (US)
- Institut thématique Génétique, génomique et bioinformatique (FR)
- HonorHealth (US)
- University of Pittsburgh Medical Center (US)
- Immunovia (Sweden) (SE)
- University of Pennsylvania (US)
- Stanford University (US)
Publication Details
- Journal
- Gastroenterology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1053/j.gastro.2025.08.034
- Citations
- 8
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 8.36
Funders
- U.S. Department of Defense
- National Institutes of Health
- Knight Cancer Institute, Oregon Health and Science University
- National Cancer Institute