Immunotherapy-Based Strategies versus Transcatheter Arterial Chemoembolization and the Impact of Treatment Duration in Hepatocellular Carcinoma with Microvascular Invasion: A Retrospective Multicenter Cohort Study
Among patients with HCC and MVI following curative resection, adjuvant ICIs therapy provides a significant recurrence-free survival advantage over TACE. Treatment durations shorter than 12 months may be insufficient, supporting the benefit of prolonged therapy.
Authors
- Dandan Hu (ORCID: https://orcid.org/0000-0001-7905-8536)
- Xueshuai Wan (ORCID: https://orcid.org/0000-0003-2140-5384)
- Jie Pan (ORCID: https://orcid.org/0000-0002-7431-9837)
- Yaojun Zhang (ORCID: https://orcid.org/0000-0002-9752-4729)
- Xiaokun Chen (ORCID: https://orcid.org/0000-0001-5784-7411)
- Huay Cheem Tan (ORCID: https://orcid.org/0000-0001-7372-4702)
- Xiao Liu (ORCID: https://orcid.org/0000-0001-5173-6075)
- Shunda Du (ORCID: https://orcid.org/0000-0002-9357-3259)
- Mei Guan (ORCID: https://orcid.org/0000-0001-5929-7142)
- Wei Peng (ORCID: https://orcid.org/0000-0002-5780-2157)
- Ziyue Huang (ORCID: https://orcid.org/0000-0001-7336-7370)
- Yilei Mao (ORCID: https://orcid.org/0000-0003-0449-4223)
- Jiali Xing (ORCID: https://orcid.org/0000-0002-5731-0240)
- Kang Zhou (ORCID: https://orcid.org/0000-0002-7237-2247)
- Liguo Liu (ORCID: https://orcid.org/0000-0003-2674-9928)
- Xiaoyan Chang (ORCID: https://orcid.org/0000-0003-0963-642X)
- Baoluhe Zhang
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Peking Union Medical College Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/jhc.s556979
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Peking Union Medical College Hospital
- Peking Union Medical College