Prognostic relevance of PRSS2 and its immune correlates in papillary thyroid carcinoma

PRSS2 is upregulated in PTC and is associated with favorable prognosis. Its association with <i>TRBV</i> and other immune-related genes suggests a correlation with tumor immune microenvironment. Further studies are needed to elucidate the biological functions of PRSS2 in PTC and to assess therapeutic potential.

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Publication Details

Journal
Open Medicine
Published
2025-01-01
DOI
https://doi.org/10.1515/med-2025-1283
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic relevance of PRSS2 and its immune correlates in papillary thyroid carcinoma

Jianming Gong, Linwen Zeng, Ming Wu, Xiaoxiao Jiang et al.
Open Medicine
Thyroid Cancer Diagnosis and Treatment
article

Prognostic relevance of PRSS2 and its immune correlates in papillary thyroid carcinoma

Jianming Gong, Linwen Zeng, Ming Wu, Xiaoxiao Jiang, Wei Lin, Xiangdong Kong
article en

Abstract

PRSS2 is upregulated in PTC and is associated with favorable prognosis. Its association with <i>TRBV</i> and other immune-related genes suggests a correlation with tumor immune microenvironment. Further studies are needed to elucidate the biological functions of PRSS2 in PTC and to assess therapeutic potential.

Open MedicineVol. 20(1)
Jinshan Hospital of Fudan University (CN)
Openalex Percentile: Top 57%
Thyroid Cancer Diagnosis and Treatment
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