The role of FRUITFULL controlling cell cycle during early flower development revealed by time-series snRNA-seq experiments
Our work illustrates how time-series snRNA-seq experiments can be used to identify bifurcation points between regulatory programs and to identify candidate regulators on these bifurcations. In particular, we identify the regulation of KRP2 by FUL as an important regulatory point to balance cell division and developmental differentiation in plants.
Authors
- José M. Muiño (ORCID: https://orcid.org/0000-0002-6403-7262)
- Kerstin Kaufmann (ORCID: https://orcid.org/0000-0001-7960-6256)
- Crisanto Gutiérrez (ORCID: https://orcid.org/0000-0001-8905-8222)
- Cezary Smaczniak (ORCID: https://orcid.org/0000-0002-4663-8275)
- Xiaocai Xu (ORCID: https://orcid.org/0000-0002-2972-4251)
- Robert Sablowski (ORCID: https://orcid.org/0000-0002-1732-2909)
- Peilin Chen (ORCID: https://orcid.org/0000-0002-0498-8349)
- Bénédicte Desvoyes
Institutions
- John Innes Centre (GB)
- Norwich Research Park (GB)
- Federal Institute for Risk Assessment (DE)
- Humboldt-Universität zu Berlin (DE)
- Centro de Biología Molecular Severo Ochoa (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Genome biology
- Published
- 2025-10-27
- DOI
- https://doi.org/10.1186/s13059-025-03831-z
- Primary Topic
- Plant Molecular Biology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- UK Research and Innovation
- Deutsche Forschungsgemeinschaft
- Humboldt-Universität zu Berlin
- Biotechnology and Biological Sciences Research Council