Impact of the nitric oxide substrate l-arginine alone and combined with atropine on malathion neuro and hepato-toxicity

These results indicated that exogenously administered l-arginine did not protect against the neuro- and hepto-toxic effects of malathion. Meanwhile, the ability of atropine to mitigate the deleterious effects of a toxic dose of malathion provides a strong support to the role of excessive stimulation cholinergic pathways in inflicting such damage.

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Publication Details

Journal
Journal of Complementary and Integrative Medicine
Published
2025-10-27
DOI
https://doi.org/10.1515/jcim-2025-0192
Primary Topic
Nitric Oxide and Endothelin Effects
Type
article
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article

Impact of the nitric oxide substrate l-arginine alone and combined with atropine on malathion neuro and hepato-toxicity

Heba A. Farid, Nermeen Shaffie, Eman R. Youness, Omar M. E. Abdel‐Salam et al.
Journal of Complementary and Integrative Medicine
Nitric Oxide and Endothelin Effects
article

Impact of the nitric oxide substrate l-arginine alone and combined with atropine on malathion neuro and hepato-toxicity

Heba A. Farid, Nermeen Shaffie, Eman R. Youness, Omar M. E. Abdel‐Salam, Amany A. Sleem
article en

Abstract

These results indicated that exogenously administered l-arginine did not protect against the neuro- and hepto-toxic effects of malathion. Meanwhile, the ability of atropine to mitigate the deleterious effects of a toxic dose of malathion provides a strong support to the role of excessive stimulation cholinergic pathways in inflicting such damage.

Journal of Complementary and Integrative Medicine
National Research Centre (EG), National Water Research Center (EG)
Openalex Percentile: Top 61%
Nitric Oxide and Endothelin Effects
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