Integrated Multi‐Omics Analysis and Cross‐Model Validation Reveal Mitochondrial Signatures in Alzheimer's Disease
These functionally validated findings provide deeper insights into the complex mitochondrial regulatory mechanisms involved in AD pathogenesis, offering robust biomarkers and novel potential avenues for developing targeted therapeutic strategies to address this challenging neurodegenerative disease.
Authors
- Yin Shen (ORCID: https://orcid.org/0000-0001-7002-4022)
- Hao Wu (ORCID: https://orcid.org/0000-0003-4915-883X)
- Yang He (ORCID: https://orcid.org/0000-0001-9171-5500)
- Shasha Fan (ORCID: https://orcid.org/0000-0002-5975-8081)
- Li Jiang (ORCID: https://orcid.org/0000-0001-7351-1811)
- Xiangyu Meng
- Xuan Xu
- Junwen He (ORCID: https://orcid.org/0009-0002-9462-0077)
Institutions
- Sun Yat-sen University (CN)
- Anhui Medical University (CN)
- Huazhong Agricultural University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
- Minda Hospital (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1111/cns.70634
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00