Bringing Back Theorizing Medical Hypotheses to Spine Surgery Research in an Age of Overreliance on Randomized Controlled Trials
A recalibrated, hybrid evidence ecosystem-combining RCT rigor with systematically evaluated observational science-can better capture the realities of spine surgery, accelerate safe innovation, and keep patient needs at the center of evidence generation.
Authors
- Rossano Kepler Alvim Fiorelli (ORCID: https://orcid.org/0000-0001-5236-0903)
- Alexander R. Vaccaro (ORCID: https://orcid.org/0000-0002-8073-0796)
- Morgan P. Lorio (ORCID: https://orcid.org/0000-0003-1623-2095)
- Kai‐Uwe Lewandrowski (ORCID: https://orcid.org/0000-0001-7842-2914)
- Óscar L. Alves (ORCID: https://orcid.org/0000-0003-4111-9270)
- Sergio L. Schmidt (ORCID: https://orcid.org/0000-0001-7654-5507)
- Hansen A. Yuan
Institutions
- Thomas Jefferson University (US)
- SUNY Upstate Medical University (US)
- Universidade do Estado do Rio de Janeiro (BR)
- Hospital Universitário Gaffrée e Guinle (BR)
- Unidade Local de Saúde de Entre Douro e Vouga (PT)
- Desert Institute For Spine Care (US)
- Banner - University Medical Center Tucson (US)
- Lusíada University of Porto (PT)
- Cancer Institute of Florida (US)
- Fundación Universitaria Sanitas (CO)
- Orlando College of Osteopathic Medicine
- Universidade Federal do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- The International Journal of Spine Surgery
- Published
- 2025-10-01
- DOI
- https://doi.org/10.14444/8802
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00