Association between SGLT2 inhibitor use and risk of sepsis-induced cardiomyopathy in patients with type 2 diabetes: a propensity-matched cohort study

Among patients with T2D and sepsis, SGLT2is were associated with a lower risk of SICM and improved long-term cardiovascular outcomes, compared to DPP4is therapy. These results support further prospective studies to validate the role of SGLT2is in preventing SICM.

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Publication Details

Journal
Critical Care
Published
2025-10-27
DOI
https://doi.org/10.1186/s13054-025-05685-0
Citations
3
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
3.88
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article

Association between SGLT2 inhibitor use and risk of sepsis-induced cardiomyopathy in patients with type 2 diabetes: a propensity-matched cohort study

Tsung Yu, Chia‐Li Kao, Kuan‐Jui Tseng, Jheng‐Yan Wu et al.
3 citations
Critical Care
Diabetes Treatment and Management
3.88
article

Association between SGLT2 inhibitor use and risk of sepsis-induced cardiomyopathy in patients with type 2 diabetes: a propensity-matched cohort study

Tsung Yu, Chia‐Li Kao, Kuan‐Jui Tseng, Jheng‐Yan Wu, Kuo-Chuan Hung, Yu‐Min Lin
article en
3 citations

Abstract

Among patients with T2D and sepsis, SGLT2is were associated with a lower risk of SICM and improved long-term cardiovascular outcomes, compared to DPP4is therapy. These results support further prospective studies to validate the role of SGLT2is in preventing SICM.

Critical CareVol. 29(1)
E-Da Hospital (TW), Chi Mei Medical Center (TW), National Cheng Kung University (TW), I-Shou University (TW)
Openalex Percentile: Top 6%
Diabetes Treatment and Management
3.88
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Association between SGLT2 inhibitor use and risk of sepsis-induced cardiomyopathy in patients with type 2 diabetes: a propensity-matched cohort study — Tsung Yu, Chia‐Li Kao, et al. · Critical Care (2025) | TGRS Research Map | TGRS