Multifocal hemorrhagic metastases with cerebellar predominance following prolonged remission of pancreatic adenocarcinoma: illustrative case
In patients who achieve pancreatic cancer remission considering systemic therapy de-escalation, clinical vigilance remains essential. Lingering brain metastases may remain resistant and signal rapid decline, particularly in aggressive cerebellar lesions. Targeted surgical and radiosurgical approaches support the potential for individualized, lesion-specific therapy. https://thejns.org/doi/10.3171/CASE25624.
Authors
- David John (ORCID: https://orcid.org/0000-0003-3217-5449)
- David J. Coté (ORCID: https://orcid.org/0000-0001-5419-1517)
- Jason C. Ye (ORCID: https://orcid.org/0000-0001-9087-6011)
- Robert G. Briggs (ORCID: https://orcid.org/0000-0001-9329-4471)
- Jonathan Sisti (ORCID: https://orcid.org/0000-0001-9011-1668)
- Gabriel Zada (ORCID: https://orcid.org/0000-0001-5821-902X)
- David Gómez (ORCID: https://orcid.org/0000-0003-3612-661X)
Institutions
- University of Southern California (US)
- Neurological Surgery (US)
Publication Details
- Journal
- Journal of Neurosurgery Case Lessons
- Published
- 2025-10-27
- DOI
- https://doi.org/10.3171/case25624
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00