The effectiveness of hydrogel matrix containing nitric oxide, silver nanoparticles, vancomycin, and ciprofloxacin on methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa biofilm isolated from patients with chronic rhinosinusitis
Our findings illustrated the efficacy of employing HyNSVC for drug release regulation and antibiofilm activity for bacterial infection, suggesting a promising treatment for CRS.
Authors
- Zahra Chegini (ORCID: https://orcid.org/0000-0003-2382-3846)
- Mohammad Yousef Alikhani (ORCID: https://orcid.org/0000-0003-4577-4029)
- Mohammad Reza Arabestani (ORCID: https://orcid.org/0000-0001-9991-8193)
- Aref Shariati (ORCID: https://orcid.org/0000-0003-1680-0427)
- Shahin Rajaeih (ORCID: https://orcid.org/0000-0002-8673-2469)
- Mehdi Azizi
- Maliheh Safaiee
Institutions
- Hamedan University of Medical Sciences (IR)
- Arak University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
- Bu-Ali Sina University (IR)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1186/s40001-025-03282-z
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hamadan University of Medical Sciences