Salivary and Serum Cytokine Levels in Oral Chronic Graft‐Versus‐Host Disease: A Longitudinal Study on the Role of <scp>IL</scp> ‐6, <scp>IL</scp> ‐1α, and <scp>IL</scp> ‐17
While IL-6 and IL-17 play roles in cGVHD, only IL-17 showed significant reduction after topical steroid therapy. This suggests IL-17's potential as a marker for inflammatory activity in cGVHD. Serum IL-17 may serve as a useful biomarker in oral cGVHD. Future studies with larger cohorts are needed to further validate these findings and explore the role of salivary cytokines in disease monitoring.
Authors
- Anna Caretti (ORCID: https://orcid.org/0000-0001-6140-6969)
- Fabiana Allevi (ORCID: https://orcid.org/0000-0002-5012-4031)
- G Ghilardi (ORCID: https://orcid.org/0000-0002-0269-5761)
- Alberto Maria Saibene (ORCID: https://orcid.org/0000-0003-1457-6871)
- Letizia Nitro (ORCID: https://orcid.org/0000-0002-0236-8728)
- Giovanni Felisati (ORCID: https://orcid.org/0000-0001-6763-4305)
- Federico Biglioli (ORCID: https://orcid.org/0000-0003-4882-7595)
- Linda Montavoci (ORCID: https://orcid.org/0000-0001-7484-5311)
- Giorgia Pugliese (ORCID: https://orcid.org/0009-0000-6979-4206)
- Matilde Coccapani
- Francesco Ferella (ORCID: https://orcid.org/0009-0006-5555-4029)
Institutions
- AOL (United States) (US)
- University of Milan (IT)
- Ospedale San Paolo (IT)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1111/jop.70076
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00