Case Report: Exogenous insulin antibody syndrome complicated with chronic renal failure and long-term history of type 2 diabetes: report of two cases
In both patients, glycemic fluctuations resolved following insulin discontinuation and the initiation of dorzagliatin, confirming the diagnosis of EIAS. In type 2 diabetic patients with unexplained hypoglycemic and hyperglycemic episodes with a history of exogenous insulin use, pancreatic function and the autoimmune antibody spectrum should be comprehensively evaluated to rule out EIAS and provide an accurate diagnosis and guide treatment strategies.
Authors
- Xiaozhu Huang (ORCID: https://orcid.org/0000-0003-1165-0749)
- Jun Pan (ORCID: https://orcid.org/0000-0002-5091-982X)
- Zhiwei Hu (ORCID: https://orcid.org/0000-0003-3337-209X)
- Hua Dong
Institutions
- First Hospital of Jiaxing (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fendo.2025.1676062
- Citations
- 1
- Primary Topic
- Diabetes Management and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.29