Case Report: Exogenous insulin antibody syndrome complicated with chronic renal failure and long-term history of type 2 diabetes: report of two cases

In both patients, glycemic fluctuations resolved following insulin discontinuation and the initiation of dorzagliatin, confirming the diagnosis of EIAS. In type 2 diabetic patients with unexplained hypoglycemic and hyperglycemic episodes with a history of exogenous insulin use, pancreatic function and the autoimmune antibody spectrum should be comprehensively evaluated to rule out EIAS and provide an accurate diagnosis and guide treatment strategies.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-10-29
DOI
https://doi.org/10.3389/fendo.2025.1676062
Citations
1
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
1.29
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article

Case Report: Exogenous insulin antibody syndrome complicated with chronic renal failure and long-term history of type 2 diabetes: report of two cases

Xiaozhu Huang, Jun Pan, Zhiwei Hu, Hua Dong
1 citations
Frontiers in Endocrinology
Diabetes Management and Research
1.29
article

Case Report: Exogenous insulin antibody syndrome complicated with chronic renal failure and long-term history of type 2 diabetes: report of two cases

Xiaozhu Huang, Jun Pan, Zhiwei Hu, Hua Dong
article en
1 citations

Abstract

In both patients, glycemic fluctuations resolved following insulin discontinuation and the initiation of dorzagliatin, confirming the diagnosis of EIAS. In type 2 diabetic patients with unexplained hypoglycemic and hyperglycemic episodes with a history of exogenous insulin use, pancreatic function and the autoimmune antibody spectrum should be comprehensively evaluated to rule out EIAS and provide an accurate diagnosis and guide treatment strategies.

Frontiers in EndocrinologyVol. 16
First Hospital of Jiaxing (CN)
Openalex Percentile: Top 14%
Diabetes Management and Research
1.29
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