Independent and joint associations of glucose modified by high-density lipoprotein cholesterol with mortality in heart failure patients: evidence from the Jiangxi, China cohort
This cohort study of the Jiangxi population in China is the first to reveal a U-shaped association between FHR and 30-day mortality in ADHF patients, establishing a synergistic effect of FPG and HDL-C on mortality risk. Based on these findings, we propose implementing a "metabolic synergistic management" strategy for ADHF patients in clinical practice.
Authors
- Guotai Sheng (ORCID: https://orcid.org/0000-0001-5298-4724)
- Hui Y. Lan
- Guobo Xie (ORCID: https://orcid.org/0000-0002-5020-4920)
- Guihua Jian (ORCID: https://orcid.org/0000-0001-5332-7638)
- Shiming He
- Juan Wang (ORCID: https://orcid.org/0000-0002-2537-1348)
- Wei Qiang Wang (ORCID: https://orcid.org/0000-0002-1430-1360)
- Fang Yan (ORCID: https://orcid.org/0000-0001-8596-3858)
- Yang Zou (ORCID: https://orcid.org/0000-0001-8948-4133)
- Kun Jiang
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fendo.2025.1680746
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province