Antibodies to myelin oligodendrocyte glycoprotein in optic perineuritis
These findings highlight distinct clinical characteristics of MOG-IgG-positive OPN, including younger age, higher relapse rates, and superior visual recovery. Detection of MOG-IgG in OPN may facilitate early diagnosis, prognosis prediction, and guide individualized therapeutic strategies.
Authors
- Chunyan Pan
- Xintong Xu (ORCID: https://orcid.org/0000-0002-6993-2020)
- Quangang Xu (ORCID: https://orcid.org/0000-0002-4507-1377)
- Shanshan Cao (ORCID: https://orcid.org/0000-0001-7280-1657)
- Huanfen Zhou (ORCID: https://orcid.org/0000-0002-8170-8195)
- Mingming Sun (ORCID: https://orcid.org/0000-0002-1990-7484)
- Yuan Zhang (ORCID: https://orcid.org/0000-0001-9747-1391)
- Yuhang Wang (ORCID: https://orcid.org/0000-0002-7290-2551)
- Shihui Wei (ORCID: https://orcid.org/0000-0003-1939-7493)
Institutions
- Chinese PLA General Hospital (CN)
- Air Force General Hospital PLA (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fimmu.2025.1657600
- Primary Topic
- IgG4-Related and Inflammatory Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- General Hospital of People’s Liberation Army