Novel deep learning-based prediction of HER2 expression in breast cancer using multimodal MRI, nomogram, and decision curve analysis
This study demonstrates that integrating deep learning with multi-sequence breast MRI and clinical data provides a highly effective and reliable tool for predicting HER2 expression in breast cancer. The model's performance, validated through rigorous evaluation, offers significant potential for clinical implementation in personalized oncology, improving decision-making and treatment planning for breast cancer patients.
Authors
- Yun Zhao (ORCID: https://orcid.org/0000-0001-7468-890X)
- Shi Qiu (ORCID: https://orcid.org/0000-0002-8027-3396)
- Qianqian Zhao (ORCID: https://orcid.org/0000-0002-9323-9007)
Institutions
- Jiangnan University (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Wuxi Fourth People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-29
- DOI
- https://doi.org/10.3389/fonc.2025.1593033
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00