Novel deep learning-based prediction of HER2 expression in breast cancer using multimodal MRI, nomogram, and decision curve analysis

This study demonstrates that integrating deep learning with multi-sequence breast MRI and clinical data provides a highly effective and reliable tool for predicting HER2 expression in breast cancer. The model's performance, validated through rigorous evaluation, offers significant potential for clinical implementation in personalized oncology, improving decision-making and treatment planning for breast cancer patients.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-10-29
DOI
https://doi.org/10.3389/fonc.2025.1593033
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
Field-Weighted Citation Impact
0.00
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article

Novel deep learning-based prediction of HER2 expression in breast cancer using multimodal MRI, nomogram, and decision curve analysis

Yun Zhao, Shi Qiu, Qianqian Zhao
Frontiers in Oncology
Radiomics and Machine Learning in Medical Imaging
article

Novel deep learning-based prediction of HER2 expression in breast cancer using multimodal MRI, nomogram, and decision curve analysis

Yun Zhao, Shi Qiu, Qianqian Zhao
article en

Abstract

This study demonstrates that integrating deep learning with multi-sequence breast MRI and clinical data provides a highly effective and reliable tool for predicting HER2 expression in breast cancer. The model's performance, validated through rigorous evaluation, offers significant potential for clinical implementation in personalized oncology, improving decision-making and treatment planning for breast cancer patients.

Frontiers in OncologyVol. 15
Jiangnan University (CN), Affiliated Hospital of Taishan Medical University (CN), Wuxi Fourth People's Hospital (CN), Shandong First Medical University (CN)
Openalex Percentile: Top 54%
Radiomics and Machine Learning in Medical Imaging
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