Efficacy and Tolerability of Seven Antipsychotic Drugs in Acutely Ill Patients With Schizophrenia: A Randomized, Multicenter, Assessor-Blinded Trial
This trial fills important knowledge gaps in acute antipsychotic treatment of schizophrenia. It confirms hierarchies in efficacy and side effects of antipsychotics from related evidence.
Authors
- Stefan Leucht (ORCID: https://orcid.org/0000-0002-4934-4352)
- Yaoyao Sun (ORCID: https://orcid.org/0000-0001-8096-3568)
- Weihua Yue (ORCID: https://orcid.org/0000-0002-1201-8465)
- Zhewei Kang (ORCID: https://orcid.org/0000-0002-3722-3713)
- Rui Yuan (ORCID: https://orcid.org/0000-0002-6603-6423)
- Dongxue Chen
- Lingjiang Li
- Xiaoyang Feng
- Yundan Liao (ORCID: https://orcid.org/0000-0002-0969-6927)
- Johannes Schneider‐Thoma (ORCID: https://orcid.org/0000-0002-3448-9532)
- Hao Yan (ORCID: https://orcid.org/0000-0003-0376-9037)
- Yunqing Zhu (ORCID: https://orcid.org/0000-0002-3183-2630)
- Zhe Lu (ORCID: https://orcid.org/0000-0003-1922-6686)
- Junyuan Sun (ORCID: https://orcid.org/0000-0002-5428-3558)
- Fude Yang (ORCID: https://orcid.org/0000-0003-1526-7755)
- Yuyanan Zhang (ORCID: https://orcid.org/0000-0002-0474-1135)
- Chuanyue Wang (ORCID: https://orcid.org/0000-0001-6549-3713)
- Yang Yang (ORCID: https://orcid.org/0000-0003-0527-5567)
- Tianlan Lu (ORCID: https://orcid.org/0009-0000-7839-4642)
- Wuxiang Xie (ORCID: https://orcid.org/0000-0001-7527-1022)
- Dai Zhang
- Jing Guo
- Guorui Zhao (ORCID: https://orcid.org/0000-0003-3097-3797)
- Tao Li (ORCID: https://orcid.org/0000-0003-3079-481X)
Institutions
- Central South University (CN)
- McGovern Institute for Brain Research (US)
- Peking University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Beijing Anding Hospital (CN)
- German Center for Infection Research (DE)
- Chinese Institute for Brain Research (CN)
- Institute of Clinical Research (US)
- German Centre for Cardiovascular Research (DE)
- Hangzhou Seventh Peoples Hospital (CN)
- Beijing HuiLongGuan Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Peking University Sixth Hospital (CN)
- Technical University of Munich (DE)
Publication Details
- Journal
- American Journal of Psychiatry
- Published
- 2025-10-29
- DOI
- https://doi.org/10.1176/appi.ajp.20250111
- Citations
- 6
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.83