Maresin-1 alleviates sepsis-induced acute kidney injury by inhibiting ferroptosis via the Nrf2/HO-1/Gpx4 signaling pathway
This study demonstrates that MaR-1 alleviates S-AKI by inhibiting ferroptosis through activation of theNrf2/HO-1/GPx4 signaling pathway. These findings provide insights into the potential therapeutic application of MaR-1 for S-AKI.
Authors
- Lili Tang (ORCID: https://orcid.org/0000-0003-1524-4617)
- Yuhao Wang (ORCID: https://orcid.org/0000-0002-9697-0137)
- Ping Wan (ORCID: https://orcid.org/0000-0001-6888-4701)
- Xiaoxia Gou (ORCID: https://orcid.org/0000-0002-3842-4007)
- Xiaoyue Li (ORCID: https://orcid.org/0000-0001-9149-7152)
- Dongrui He
Institutions
- Macau University of Science and Technology (MO)
- Sun Yat-sen University (CN)
- Zunyi Medical University (CN)
- Zhuhai People's Hospital (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-10-28
- DOI
- https://doi.org/10.1080/0886022x.2025.2575112
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04