Correction of Reward Processing Deficits in Youth with Disruptive Behavior and Trauma Exposure: A Pilot Study of Neural Responses to Fluoxetine
We provide preliminary data suggesting that a serotonergic medication can correct reward processing and provide symptom improvement in youth with DBDs and a history of trauma exposure. Given the small sample size, more rigorous studies with larger sample size are needed to confirm these results. The findings of this study could aid future clinical research and treatment for this challenging population.
Authors
- Soonjo Hwang (ORCID: https://orcid.org/0000-0001-5117-2468)
- Ellen Leibenluft (ORCID: https://orcid.org/0000-0001-8971-2087)
- Ji‐Woo Seok (ORCID: https://orcid.org/0000-0001-5690-2802)
- Stuart F. White (ORCID: https://orcid.org/0000-0002-4713-9267)
- Un‐Sun Chung (ORCID: https://orcid.org/0000-0003-3871-1425)
- James Blair (ORCID: https://orcid.org/0000-0002-6377-2361)
Institutions
- Mental Health Services (DK)
- Families USA (US)
- Kyungpook National University (KR)
- Korea Institute of Oriental Medicine (KR)
- National Institute of Mental Health (US)
- University of Nebraska Medical Center (US)
Publication Details
- Journal
- Clinical Psychopharmacology and Neuroscience
- Published
- 2025-10-29
- DOI
- https://doi.org/10.9758/cpn.25.1336
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00