N-Heterocyclic carbene-catalyzed asymmetric synthesis of bis-ferrocene derivatives bearing two stereogenic planes

The synthesis of ferrocene derivatives with dual planar chirality remains a significant challenge in asymmetric catalysis. This study presents an enantio- and diastereoselective N-heterocyclic carbene-catalyzed strategy to construct such compounds <i>via</i> a double desymmetrization reaction. Synthetic applications highlighted the versatility of these planar-planar chiral products in asymmetric synthesis as catalysts.