The clinical value of metagenomic next-generation sequencing for diagnosing pulmonary infections in kidney transplant recipients
This study offers preliminary insights into the spectrum of pathogens responsible for pulmonary infections following kidney transplantation, laying the foundation for better understanding their clinical characteristics. In patients with post-transplant pulmonary infections, metagenomic NGS outperforms conventional detection methods in terms of pathogen detection, speed, positivity rate, sensitivity, and ability to diagnose mixed infections.
Authors
- Panyan Liu
- Zhenfeng Deng (ORCID: https://orcid.org/0009-0006-3881-9312)
- Dao‐Pei Lu
- Zhiang Liu (ORCID: https://orcid.org/0009-0008-6892-1355)
- Chunhong Li (ORCID: https://orcid.org/0000-0002-3949-8462)
- Xiaohong Qin (ORCID: https://orcid.org/0009-0006-7528-6869)
- Tingting Lu (ORCID: https://orcid.org/0000-0001-6998-5969)
Institutions
- Kingmed Diagnostics (CN)
- The Second Nanning People's Hospital (CN)
- First People's Hospital of Nanning (CN)
- 303 Hospital of People's Liberation Army (CN)
Publication Details
- Journal
- Laboratory Medicine
- Published
- 2025-06-06
- DOI
- https://doi.org/10.1093/labmed/lmaf035
- Citations
- 1
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35