Polygenic Risk Scores Predicting Estimated GFR Validated With Iohexol Clearance

SNVs with non-GFR effects on creatinine and cystatin-C influence GWAS results. The results of GWAS using eGFR should be validated using experimental and other more precise methods.

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Publication Details

Journal
Kidney International Reports
Published
2025-10-29
DOI
https://doi.org/10.1016/j.ekir.2025.10.016
Primary Topic
Chronic Kidney Disease and Diabetes
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article
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article

Polygenic Risk Scores Predicting Estimated GFR Validated With Iohexol Clearance

Stein Hallan, Viji Nair, Inger Therese Enoksen, Toralf Melsom et al.
Kidney International Reports
Chronic Kidney Disease and Diabetes
article

Polygenic Risk Scores Predicting Estimated GFR Validated With Iohexol Clearance

Stein Hallan, Viji Nair, Inger Therese Enoksen, Toralf Melsom, Ludvig Balteskard Rinde, M. Kretzler, Björn O. Eriksen, Jon V.N. Porserud
article en

Abstract

SNVs with non-GFR effects on creatinine and cystatin-C influence GWAS results. The results of GWAS using eGFR should be validated using experimental and other more precise methods.

Kidney International ReportsVol. 11(1)
University Hospital of North Norway (NO), Norwegian University of Science and Technology (NO), University of Michigan (US), St Olav's University Hospital (NO), UiT The Arctic University of Norway (NO)
Openalex Percentile: Top 63%
Chronic Kidney Disease and Diabetes
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Polygenic Risk Scores Predicting Estimated GFR Validated With Iohexol Clearance — Stein Hallan, Viji Nair, et al. · Kidney International Reports (2025) | TGRS Research Map | TGRS